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Course Info

About this Course

This course will interactively engage the students cognitively and scientifically in the areas of natural product chemistry including definition of natural products, metabolism, and their classes. The students will be exposed to natural products approach to drug discovery including sampling, vouchering, extraction and isolation of secondary metabolites from natural products. The outcomes shall be assessed through a variety of tools which include the traditional paper examination (tests and final examination), classroom engagement like student presentation and case study report.

Course Syllabus

Introduction to Natural Product Chemistry
Definition
Primary metabolism
Secondary metabolism
Sources of natural products
Ethnobotany and traditional uses of natural products

Classification of Natural Products
Introduction
Terpenes
Alkaloids
Flavonoids
Other compounds

Extraction, isolation and characterization of natural products
Collection, storage and vouchering of plant samples
Extraction and pretreatment of plant samples
Detection methods for secondary metabolites
Isolation of natural products
Characterization of natural products

Natural products approach to drug discovery
Drug development from natural products
Plant cell biotechnology
Biocatalysis as a tool of natural product production
Herbal Analysis
Metabolomics

Case studies
Anticancer drugs
Antimalarial drug
Antibacterial drug
Botanical drug
Others

Frequently Asked Questions

Q1 : What is natural products?
A1 : Natural products are chemicals produced by living things.

Q2 : How natural products are isolated and characterized?
A2 : Natural products are isolated using various chromatographic procedures such as HPLC and PLC and characterized using modern spectroscopic techniques such as NMR and LCMS.