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Course Info

About this Course

This course will provide the student with a background in the science of toxicology. Students will be exposed to the different sources of environmental pollutants in the atmosphere, soil and water, together with the effects of these environmental chemical pollutants on organs and body systems. The toxic chemicals discussed include heavy metals, elemental forms, inorganic, pesticides, organic solvents, and gases to which the public may be exposed by way of contaminated air, water, and food.

Course Syllabus

Introduction to Toxicology
Definition, purpose, subdicipline and terminology
Toxicological and ecological concepts
Dose-response relationship

Absorption of toxicants
Cell membrane (passive and active transport)
Absorption of toxicant by Gastrointestinal and respiratory tract
Absorption of toxicant through skin and by special routes

Distribution and Storage of Toxicants
Volume of distribution
Storage of toxicant in tissue (plasma proteins, liver, kidney, fat and bone)
Passage of toxicant across blood brain barrier and placenta

Biotransformation
Phase I & Phase II reactions
Reaction sites
Bioactivation

Excretion of toxicants
Urinary elimination
Fecal excretion
Exhalation and other routes

Effects of toxic chemicals
Target organ toxicity
Reproductive and development toxicity
Genetic toxicity, mutagenesis and Chemical Carcinogenesis

Environmental toxicants
Heavy metals and Pesticides
Organic compounds and Plastics
Air pollutants, Food additives and others

Frequently Asked Questions

Q1 : Is it compulsory to complete this MOOC?
A1 : Only by completing this MOOC, you will be awarded with the certificate of completion.